Hydrochloric Acid → HCID 66995605, compound

HRID 1675606Notes

Reaction equation

HRID 1675606 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][CH3:21])=[C:6]([S:8][C:9]2[CH:19]=[CH:18][C:12]([C:13]([O:15]CC)=[O:14])=[CH:11][CH:10]=2)[CH:7]=1.[OH-].[Li+].Cl>CO.O>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:20][CH3:21])=[C:6]([S:8][C:9]2[CH:19]=[CH:18][C:12]([C:13]([OH:15])=[O:14])=[CH:11][CH:10]=2)[CH:7]=1

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 3939Lithium HydroxideHCID 66996055HCID 66996055, compound

Product 1

HCID 66995605HCID 66995605, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

A mixture of the product from step (i) (0.24 g), lithium hydroxide (0.036 g) in methanol (30 ml) and water (5 ml) was stirred at RT overnight then acidified with 2M hydrochloric acid. The mixture was extracted with ethylacetate, the organics dried and evaporated under reduced pressure, yield 0.23 g

Workup

  1. extractionThe mixture was extracted with ethylacetate
  2. customthe organics dried
  3. customevaporated under reduced pressure, yield 0.23 g

Sources & evidence

ORD record
ord-8435276dcd17432091ab2422aa06a5b7
Source dataset
uspto-grants-2011_08
Patent number
US08003703B2

Reaction notes

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