Tetrahydrofuran → ethyl 3-[2-fluoro-4-({4'-[(4-hydroxytetrahydro-2H-thiopyran-4-yl)methoxy]-2',6'-dimethylbiphenyl-3-yl}methoxy)phenyl]propanoate
Reaction equation
[CH2:41]([P:42]([CH2:43][CH2:44][CH2:45][CH3:46])[CH2:47][CH2:48][CH2:49][CH3:50])[CH2:51][CH2:52][CH3:53].[F:26][c:27]1[c:28]([CH2:34][CH2:35][C:36](=[O:37])[O:38][CH2:39][CH3:40])[cH:29][cH:30][c:31]([OH:33])[cH:32]1.[N:54]([C:55]([N:56]1[CH2:57][CH2:58][CH2:59][CH2:60][CH2:61]1)=[O:62])=[N:63][C:64]([N:65]1[CH2:66][CH2:67][CH2:68][CH2:69][CH2:70]1)=[O:71].[O:72]1[CH2:73][CH2:74][CH2:75][CH2:76]1.[OH:1][CH2:2][c:3]1[cH:4][c:5](-[c:9]2[c:10]([CH3:25])[cH:11][c:12]([O:16][CH2:17][C:18]3([OH:24])[CH2:19][CH2:20][S:21][CH2:22][CH2:23]3)[cH:13][c:14]2[CH3:15])[cH:6][cH:7][cH:8]1>>[O:1]([CH2:2][c:3]1[cH:4][c:5](-[c:9]2[c:10]([CH3:25])[cH:11][c:12]([O:16][CH2:17][C:18]3([OH:24])[CH2:19][CH2:20][S:21][CH2:22][CH2:23]3)[cH:13][c:14]2[CH3:15])[cH:6][cH:7][cH:8]1)[c:31]1[cH:30][cH:29][c:28]([CH2:34][CH2:35][C:36](=[O:37])[O:38][CH2:39][CH3:40])[c:27]([F:26])[cH:32]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f1af3cebbe7d4510bf53d17d29416dfb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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