HRID1676938

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID712

Formaldehyde

CH2O

HCID887

Methanol

CH4O

结构：NS(=O)(=O)c1cc(-c2nn[nH]n2)c(NCc2cccs2)cc1Cl

HCID2273

Azosemide

C12H11ClN6O2S2

HCID6228

N,N-Dimethylformamide

C3H7NO

PRODUCTS

生成物

结构：COCn1nnnc1-c1cc(S(N)(=O)=O)c(Cl)cc1NCc1cccs1

HCID60208424

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

溶剂HCID22350042

未命名化合物

PROCEDURE

实验过程

Azosemide can be reacted with formaldehyde and methanol in methylene chloride, methylene chloride-DMF mixtures or DMF to yield 2-chloro-5-[1-(methoxymethyl)-1H-tetrazol-5-yl]-4-[(2-thienylmethyl)amino]benzenesulfonamide.