p-Bromobenzenesulfonyl chloride → HCID 67372575, compound

HRID 1677008Notes

Reaction equation

HRID 1677008 reaction equation
Cl.[NH2:2][CH2:3][CH2:4][NH:5][S:6]([C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([Br:18])[CH:16]=2)[N:11]([S:19]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)(=[O:21])=[O:20])[C:10]=1[C:28]([O:30][CH2:31][CH3:32])=[O:29])(=[O:8])=[O:7].[Br:33][C:34]1[CH:39]=[CH:38][C:37]([S:40](Cl)(=[O:42])=[O:41])=[CH:36][CH:35]=1>C(N(CC)CC)C>[Br:18][C:15]1[CH:16]=[C:17]2[C:12](=[CH:13][CH:14]=1)[N:11]([S:19]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)(=[O:21])=[O:20])[C:10]([C:28]([O:30][CH2:31][CH3:32])=[O:29])=[C:9]2[S:6]([NH:5][CH2:4][CH2:3][NH:2][S:40]([C:37]1[CH:38]=[CH:39][C:34]([Br:33])=[CH:35][CH:36]=1)(=[O:42])=[O:41])(=[O:8])=[O:7]

Participants

4

Reactant 2

HCID 7396p-Bromobenzenesulfonyl chlorideHCID 67373781HCID 67373781, compound

Product 1

HCID 67372575HCID 67372575, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

A solution of the product from Example 89 Step A, was combined with 4-bromobenzenesulfonyl chloride and triethylamine, and stirred at room temperature for 35 minutes. The solvent was removed with a stream of nitrogen to give the titled compound. ESI+ MS: 750 [M+H]+.

Workup

  1. customThe solvent was removed with a stream of nitrogen

Sources & evidence

ORD record
ord-21eeb2b973264ebeaec2e2dc1bc7d738
Source dataset
uspto-grants-2011_08
Patent number
US08008295B2

Reaction notes

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