Phenethylamine → HCID 57571674, compound

HRID 1677116Notes

Reaction equation

HRID 1677116 reaction equation
CO[C:3](=[O:11])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][C:5]=1Cl.[N:12]1([CH2:18][CH2:19][CH2:20][NH2:21])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1.[CH2:22]([NH2:30])[CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[N:12]1([CH2:18][CH2:19][CH2:20][NH:21][C:5]2[N:6]=[CH:7][CH:8]=[CH:9][C:4]=2[C:3]([NH:30][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)=[O:11])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1

Participants

4

Reactant 3

HCID 1001PhenethylamineHCID 61055N-(3-Aminopropyl)morpholineHCID 819931Methyl 2-chloronicotinate

Product 1

HCID 57571674HCID 57571674, compound

Procedure

The title compound was prepared in analogy to example 1, but starting from 2-chloro-nicotinic acid methyl ester and subsequently using 3-morpholin-4-yl-propylamine in the first step and phenethylamine in the third step.

Sources & evidence

ORD record
ord-6eb39e8598634dba9a7080d1f2b962aa
Source dataset
uspto-grants-2011_08
Patent number
US08008305B2

Reaction notes

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