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HRID1677373

反应详情

EQUATION

反应方程式

HRID 1677373 的结构方程式

REACTANTS

反应物

2
结构：Cl.NC1CCCOC1
HCID46735995

Oxan-3-amine--hydrogen chloride (1/1)

C5H12ClNO

结构：COc1cc(-c2cnc3[nH]cc(C(=O)O)c3n2)cc(OC)c1OC
HCID59540796

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(-c2cnc3[nH]cc(C(=O)NC4CCCOC4)c3n2)cc(OC)c1OC
HCID44207430

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CN(C)c1ccncc1
催化剂HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

结构：CCN(CC)CC
溶剂HCID8471

Triethylamine

C6H15N

PROCEDURE

实验过程

2-(3,4,5-Trimethoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid (tetrahydro-pyran-3-yl)-amide was prepared starting from 2-(3,4,5-trimethoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid and tetrahydro-pyran-3-ylamine hydrochloride following the general procedures described in these Examples but with triethylamine and DMAP added. MP 191-192° C., M+H 413.

WORKUP

后处理

  1. additionadded