Dimethylformamide → 8-[[1-(2-Cyclopropylacetyl)-4-phenylpyrrolidin-3-yl]methyl]-2-[(4-methoxyphenyl)methyl]-2,8-diazaspiro[4.5]decan-1-one
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]2[C:9](=[O:30])[C:10]3([CH2:11][CH2:12]2)[CH2:13][CH2:14][N:15]([CH2:18][CH:19]2[CH2:20][NH:21][CH2:22][CH:23]2[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:16][CH2:17]3)[cH:31][cH:32]1.[CH3:46][N:47]([c:48]1[cH:49][cH:50][n:51][cH:52][cH:53]1)[CH3:54].[CH:33]1([CH2:36][CH2:37][C:38]([OH:39])=[O:40])[CH2:34][CH2:35]1.[O:41]=[CH:42][N:43]([CH3:44])[CH3:45]>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]2[C:9](=[O:30])[C:10]3([CH2:11][CH2:12]2)[CH2:13][CH2:14][N:15]([CH2:18][CH:19]2[CH2:20][N:21]([C:37]([CH2:36][CH:33]4[CH2:34][CH2:35]4)=[O:41])[CH2:22][CH:23]2[c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[CH2:16][CH2:17]3)[cH:31][cH:32]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2f668fe557cd4c59a424d60b1a933301
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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