Hydrochloric Acid → 2-Chloro-1-[2-[[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxymethyl]pyrrolidin-1-yl]ethanone
Reaction equation
[CH2:44]([Cl:45])[Cl:46].[CH:30]([N:31]([CH:32]([CH3:33])[CH3:34])[CH2:35][CH3:36])([CH3:37])[CH3:38].[Cl:2][c:3]1[c:4]([F:29])[c:5]([NH:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:24][CH3:25])[c:14]([O:17][CH2:18][CH:19]4[NH:20][CH2:21][CH2:22][CH2:23]4)[cH:15][c:16]23)[cH:26][cH:27][cH:28]1.[Cl:39][CH2:40][C:41](=[O:42])[Cl:43].[ClH:1]>>[Cl:2][c:3]1[c:4]([F:29])[c:5]([NH:6][c:7]2[n:8][cH:9][n:10][c:11]3[cH:12][c:13]([O:24][CH3:25])[c:14]([O:17][CH2:18][CH:19]4[N:20]([C:41]([CH2:40][Cl:39])=[O:42])[CH2:21][CH2:22][CH2:23]4)[cH:15][c:16]23)[cH:26][cH:27][cH:28]1Participants
6
Sources & evidence
- ORD record
- ord-f1f2a9f6111b403aa09fe9921b2e2985
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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