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HRID1679595

反应详情

EQUATION

反应方程式

HRID 1679595 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CN(C)O
HCID27970

Methanamine, N-hydroxy-N-methyl-

C2H7NO

结构：Fc1ccc2c(c1)C(c1ccccc1)=NCc1nnc(CBr)n1-2
HCID23337462

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)Cc1nnc2n1-c1ccc(F)cc1C(c1ccccc1)=NC2
HCID23463946

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

In the manner given in Example 16, a solution of N,N-dimethylhydroxylamine in dimethylformamide is treated with sodium hydride suspended in mineral oil, and the mixture is treated with 8-fluoro-1-(bromomethyl)6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine to give 8-fluoro-1-[(dimethylamino)methyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine, N1 -oxide.