HRID1679794

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID702

Ethanol

C2H6O

HCID962

Water

H2O

HCID6961

Pyromellitic acid

C10H6O8

结构：C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccc(OC)cc12

HCID3034034

Quinine

C20H24N2O2

PRODUCTS

生成物

结构：C=C[C@H]1CN2CC[C@H]1C[C@H]2[C@H](O)c1ccnc2ccc(OC)cc12.O=C([O-])c1cc(C(=O)[O-])c(C(=O)[O-])cc1C(=O)[O-]

HCID86737755

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1031

1-Propanol

C3H8O

CONDITIONS

反应条件

温度: 80 °C

PROCEDURE

实验过程

Four grams of quinine, 2.6 g. pyromellitic acid and 50.0 g. H2O were combined with stirring and heated to 80° C. 310.0 cc ethanol and 5.0 cc n-propanol were added and the mixture held at 70°-80° C. for about 30 minutes. The reaction product was filtered hot and 3.62 g. of dry cake, M.P. 220° C. (not sharp) was obtained.

WORKUP

后处理

filtrationThe reaction product was filtered hot
customof dry cake, M.P. 220° C. (not sharp) was obtained

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cfa69825c90f45208aaf6fd5ff7d6e6c
来源数据集: uspto-grants-1981_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04270841
来源说明: uspto-grants-1981_06

反应 SMILES

[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[N:12]=[CH:11][CH:10]=[C:9]([C@@H:13]([OH:24])[C@H:14]3[N:19]4[CH2:20][C@H:21]([CH:22]=[CH2:23])[C@@H:16]([CH2:17][CH2:18]4)[CH2:15]3)[C:7]=2[CH:8]=1.[C:25]([OH:42])(=[O:41])[C:26]1[C:27](=[CH:31][C:32](=[C:36]([CH:40]=1)[C:37]([OH:39])=[O:38])[C:33]([OH:35])=[O:34])[C:28]([OH:30])=[O:29].O.C(O)C>C(O)CC>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]2[N:12]=[CH:11][CH:10]=[C:9]([C@@H:13]([OH:24])[C@H:14]3[N:19]4[CH2:20][C@H:21]([CH:22]=[CH2:23])[C@@H:16]([CH2:17][CH2:18]4)[CH2:15]3)[C:7]=2[CH:8]=1.[C:33]([O-:35])(=[O:34])[C:32]1[C:36](=[CH:40][C:26](=[C:27]([CH:31]=1)[C:28]([O-:30])=[O:29])[C:25]([O-:42])=[O:41])[C:37]([O-:39])=[O:38]