Diethylamine → HCID 23459039, compound

HRID 1680068Notes

Reaction equation

HRID 1680068 reaction equation
Cl[CH2:2][CH2:3][O:4][C:5]([O:20][CH2:21][CH2:22]Cl)([C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:13])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[CH2:24]([NH:26][CH2:27][CH3:28])[CH3:25]>CCOCC>[CH2:24]([N:26]([CH2:27][CH3:28])[CH2:2][CH2:3][O:4][C:5]([O:20][CH2:21][CH2:22][N:26]([CH2:27][CH3:28])[CH2:24][CH3:25])([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)[C:12]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:13])[CH3:25]

Participants

4

Reactant 2

HCID 8021DiethylamineHCID 14762563HCID 14762563, compound

Product 1

HCID 23459039HCID 23459039, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

20 g (0.057 mole) of benzil-di-(2-chloroethyl)ketal are stirred with 150 g (2.05 moles) of diethylamine for 24 hours at 140° C. in a pressure autoclave. After cooling, the reaction mixture is taken up in ether and extracted with water. The ether layer is dried over Na2SO4 and concentrated. The residual oil is dried in a high vacuum.

Workup

  1. temperatureAfter cooling
  2. extractionextracted with water
  3. dry with materialThe ether layer is dried over Na2SO4
  4. concentrationconcentrated
  5. customThe residual oil is dried in a high vacuum

Sources & evidence

ORD record
ord-178d4f4836a642cba39ac1cd679654da
Source dataset
uspto-grants-1981_06
Patent number
US04271294

Reaction notes

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