Methylamine → HCID 12876310, compound

HRID 1680205Notes

Reaction equation

HRID 1680205 reaction equation
[CH3:1][C:2]1([C:15]([O:17]C)=O)[C:7]2[NH:8][C:9]3[C:14]([C:6]=2[CH2:5][CH2:4][NH:3]1)=[CH:13][CH:12]=[CH:11][CH:10]=3.[CH3:19][NH2:20]>C(O)C>[CH3:1][C:2]1([C:15]([NH:20][CH3:19])=[O:17])[C:7]2[NH:8][C:9]3[C:14]([C:6]=2[CH2:5][CH2:4][NH:3]1)=[CH:13][CH:12]=[CH:11][CH:10]=3

Participants

4

Reactant 2

HCID 6329MethylamineHCID 149110Methyl 2,3,4,9-tetrahydro-1-methyl-1H-pyrido[3,4-b]indole-1-carboxylate

Product 1

HCID 12876310HCID 12876310, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4.8 g (0.02 mol) of methyl 1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate are dissolved in 100 ml of ethanol saturated with methylamine. The solution is left at ambient temperature for 48 hours. The solvent is removed and the residue is then taken up in 20 ml of ethanol. The product is filtered off and washed with ethanol.

Workup

  1. customThe solvent is removed
  2. filtrationThe product is filtered off
  3. washwashed with ethanol

Sources & evidence

ORD record
ord-06199cb348db45458e575e60b24f2ae9
Source dataset
uspto-grants-1981_06
Patent number
US04272539

Reaction notes

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