Ethyl Acetate → HCID 22816297, compound

HRID 1680209Notes

Reaction equation

HRID 1680209 reaction equation
C(OCC)(=O)C.[Cl:7][C:8]([Cl:32])([Cl:31])[CH2:9][O:10][C:11]([NH:13][C@H:14]([C:28]([OH:30])=[O:29])[CH2:15][CH2:16][CH2:17][CH2:18][NH:19][C:20]([O:22][CH2:23][C:24]([Cl:27])([Cl:26])[Cl:25])=[O:21])=[O:12].O[N:34]1[C:38](=[O:39])[CH2:37][CH2:36][C:35]1=[O:40].[K+].[Br-]>CCO>[Cl:7][C:8]([Cl:31])([Cl:32])[CH2:9][O:10][C:11]([NH:13][C@H:14]([C:28]([O:30][CH:36]1[CH2:37][C:38](=[O:39])[NH:34][C:35]1=[O:40])=[O:29])[CH2:15][CH2:16][CH2:17][CH2:18][NH:19][C:20]([O:22][CH2:23][C:24]([Cl:27])([Cl:26])[Cl:25])=[O:21])=[O:12]

Participants

6

Reactant 4

HCID 8857Ethyl AcetateHCID 80170N-HydroxysuccinimideHCID 253877Potassium BromideHCID 22816296HCID 22816296, compound

Product 1

HCID 22816297HCID 22816297, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In a manner similar to Example 2A, utilizing anhydrous ethyl acetate as the solvent, N,N'-bis-trichloroethoxycarbonyl-L-lysine is reacted with N-hydroxy succinimide to obtain the above named compound; [α]D26 -19.6° (EtOH); νmax (KBr) 1820, 1785, 1715 cm-1.

Workup

  1. customto obtain the above named compound

Sources & evidence

ORD record
ord-09b0435de0f54b37920f936fa2eb3d56
Source dataset
uspto-grants-1981_06
Patent number
US04272525

Reaction notes

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