Sulfuric Acid → 4-Hydroxybenzaldehyde

HRID 1680553Notes

Reaction equation

HRID 1680553 reaction equation
N[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.S(=O)(=O)(O)[OH:11]>CN(C)C=O>[OH:11][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 111584-Aminobenzaldehyde

Product 1

HCID 1264-HydroxybenzaldehydeYield 23%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The procedure of Example 1 was repeated except that the N,N-dimethylformamide was not added and p-aminobenzaldehyde was reacted with sulphuric acid in 40% aqueous solution at 40° C. for one hour, to obtain p-hydroxybenzaldehyde in a yield of 23%, based on the weight of p-nitrotoluene used.

Workup

  1. additionwas not added

Sources & evidence

ORD record
ord-0382e662b38a4136942b1872cea9770f
Source dataset
uspto-grants-1981_06
Patent number
US04273941

Reaction notes

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