Clavulanic Acid → HCID 22807221, compound

HRID 1680640Notes

Reaction equation

HRID 1680640 reaction equation
[CH2:1]1[C:4](=[O:5])[N:3]2[C@@H:6](C(O)=O)/[C:7](/[O:11][C@H:2]12)=[CH:8]/[CH2:9]O>O1CCCC1>[O:5]=[C:4]1[N:3]2[C@H:2]([O:11][C:7]([CH:8]=[CH2:9])=[CH:6]2)[CH2:1]1

Participants

3

Reactant 1

HCID 5280980Clavulanic Acid

Product 1

HCID 22807221HCID 22807221, compoundYield 83.3%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

(5R)-7-Oxo-3-vinyl-4-oxa-1-azabicyclo[3.2.0]hept-2-ene (ca 2.5 mmole) in tetrahydrofuran (20 ml) was prepared from clavulanic acid (3.0 mmole) as described in Example 1.

Sources & evidence

ORD record
ord-2c4dc361448b4461ab9b734b2517a92a
Source dataset
uspto-grants-1981_06
Patent number
US04275067

Reaction notes

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