反应详情

A mixture of 3.9 g. of 4-[6-(4-hydroxyphenyl)hexyl]-3,5-heptanedione, 12 g. of 2-bromoethyl ethyl ether, 4 g. of potassium carbonate and 1 g. of potassium iodide in 40 ml. of acetone was heated at reflux for 48 hours and then allowed to stand at room temperature for three days. The reaction mixture was then filtered and concentrated to remove the solvent. The residue was distilled at 200°-205° C. (0.001 mm.) to give 4-{6-[4-(2-ethoxyethoxy)phenyl]hexyl}-3,5-heptanedione as a light yellow oil.

1. additionA mixture of 3.9 g
2. temperatureat reflux for 48 hours
3. filtrationThe reaction mixture was then filtered
4. concentrationconcentrated
5. customto remove the solvent
6. distillationThe residue was distilled at 200°-205° C. (0.001 mm.)