Sodium ion → α,α-Bis(4-chlorophenyl)-4-piperidinemethanol

HRID 168083Notes

Reaction equation

HRID 168083 reaction equation
[Al+3:2].[Cl:7][c:8]1[cH:9][cH:10][c:11]([C:14]([CH:15]2[CH2:16][CH2:17][N:18]([C:21]([N:22]([CH2:23][CH3:24])[CH2:25][CH3:26])=[O:27])[CH2:19][CH2:20]2)([OH:28])[c:29]2[cH:30][cH:31][c:32]([Cl:35])[cH:33][cH:34]2)[cH:12][cH:13]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[Na+:38].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1.[OH-:37].[OH2:36]>>[Cl:7][c:8]1[cH:9][cH:10][c:11]([C:14]([CH:15]2[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]2)([OH:28])[c:29]2[cH:30][cH:31][c:32]([Cl:35])[cH:33][cH:34]2)[cH:12][cH:13]1

Participants

9

Reactant 8

HCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 14698740HCID 14698740, compound

Product 1

HCID 14698743α,α-Bis(4-chlorophenyl)-4-piperidinemethanol

Sources & evidence

ORD record
ord-3cabb7386f25484087095471c8ab92ff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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