反应详情

A mixture of 5-chloro-2-nitrobenzaldehyde (5.0 g), toluene (50 ml), p-toluenesulfonic acid monohydrate (25 mg) was heated under stirring for 2 hours by dehydrating water which was formed in the course of reaction. The solvent was distilled under reduced pressure and the residue was column chromatographed (hexane/ethyl acetate: 8/1) to give 6.5 g of the pure title compound (93%).

1. temperaturewas heated
2. customwas formed in the course of reaction
3. distillationThe solvent was distilled under reduced pressure
4. customchromatographed (hexane/ethyl acetate: 8/1)