Water → 4-(N-Dodecanoylaminomethyl)-5-hydroxy-2(5H)-furanone

HRID 1681496Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1681496
[C:1]([NH:14][CH2:15][C:16]1[CH:17]=[C:18]([Si](CC)(CC)CC)[O:19][CH:20]=1)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[OH2:28].C1C(I)=C(O)C(I)=C2OC3C(C4(OC(=O)C5C(Cl)=C(Cl)C(Cl)=C(Cl)C4=5)C=12)=CC(I)=C(O)C=3I.[O:62]=O>O1CCCC1>[C:1]([NH:14][CH2:15][C:16]1[CH:20]([OH:28])[O:19][C:18](=[O:62])[CH:17]=1)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Komponenten

6

Edukt 4

HCID 962WaterHCID 977OxygenHCID 69439Rose Bengal LactoneHCID 150370504-(N-Dodecanoylaminomethyl)-2-triethylsilylfuran

Produkt 1

HCID 150370514-(N-Dodecanoylaminomethyl)-5-hydroxy-2(5H)-furanone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

A mixture of 4-(N-dodecanoylaminomethyl)-2-triethylsilylfuran (73.2 mg, 0.18 mmol), water (0.05 ml) and Rose Bengal (ca. 3 mg) in tetrahydrofuran (5 ml) was exposed to singlet oxygen at 0° for 1.5 hours. The residue, after solvent removal, was purified by chromatography on preparative silica thin layer plates (developed with ethyl acetate) to

Aufarbeitung

  1. customThe residue, after solvent removal
  2. customwas purified by chromatography on preparative silica thin layer plates (developed with ethyl acetate) to

Quellen und Nachweise

ORD-Eintrag
ord-3a7043de3e534af898502be191bf9577
Quelldatensatz
uspto-grants-1992_12
Patentnummer
US05171863

Notizen zur Reaktion

Wird geladen…