Mandelic Acid → HCID 19804837, compound

HRID 1682344Notes

Reaction equation

HRID 1682344 reaction equation
[C:1]([OH:11])(=[O:10])[CH:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)O.[CH2:12]([CH:28]([C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][C:31]=1O)[CH3:29])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>O>[C:4]1([CH:2]2[C:32]3[CH:33]=[CH:34][CH:35]=[C:30]([CH:28]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH3:29])[C:31]=3[O:11][C:1]2=[O:10])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 1292Mandelic AcidHCID 10947993HCID 10947993, compound

Product 1

HCID 19804837HCID 19804837, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.8 g (31.5 mmol) of mandelic acid and 10.4 g (30 mmol) of 1-hexadecylethylphenol are heated together at 190°-200° C. for approx. 8 hours under reduced pressure (13.3 mbar). In the course of this the water formed in the reaction is removed by distillation. When the reaction is complete, the reaction product is filtered over silica gel (hexane) and is then treated with cold hexane. The product has a melting point of 60°-62° C. and is in the form of a white powder. The yield is 7 g (=50% of theory).

Workup

  1. customis removed by distillation
  2. filtrationthe reaction product is filtered over silica gel (hexane)
  3. additionis then treated with cold hexane

Sources & evidence

ORD record
ord-b7662e72debb4eceba83f26c0f2603d8
Source dataset
uspto-grants-1992_12
Patent number
US05175312

Reaction notes

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