Hydrochloric Acid → 167263-05-0

HRID 1683008Notes

Reaction equation

HRID 1683008 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][C:11]([C:20]#[N:21])([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:22].O1CCOCC1>>[ClH:22].[C:20]([C:11]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=2)[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]1)#[N:21]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 53439111Tert-butyl 4-cyano-4-(pyridin-2-YL)piperidine-1-carboxylate

Product 1

HCID 67322272167263-05-0

Procedure

Prepare by the method of example 30.3 using 1-tert-butoxycarbonyl-4-cyano-4-(pyridin-2-yl)-piperidine (3 mmol) and HCl in dioxane (40 mmol, 4N). Concentrate the solvent in vacuo and dry under high vacuum to give the title compound.

Workup

  1. concentrationConcentrate the solvent in vacuo
  2. customdry under high vacuum

Sources & evidence

ORD record
ord-ff7271a5c2654dbe9c2463f023de724e
Source dataset
uspto-grants-1997_06
Patent number
US05635510

Reaction notes

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