Tetrahydrofuran → HCID 178478551, compound

HRID 1683300Notes

Reaction equation

HRID 1683300 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.C([N:10]([CH2:13]C)CC)C.[Ti:15](Cl)(Cl)(Cl)[Cl:16].[CH2:20]1[CH2:24][O:23][CH2:22][CH2:21]1>>[Cl-:16].[Cl-:16].[N:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[O:1][Ti+2:15][O:23][C:24]1[CH:20]=[CH:21][CH:22]=[CH:13][N:10]=1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 24193Titanium TetrachlorideHCID 178516071HCID 178516071, compound

Product 1

HCID 178478551HCID 178478551, compound

Procedure

To a solution of 0.02 moles of 2-hydroxy pyridine and 0.02 moles of triethylamine in 50 mL of THF, a solution of 0.01 moles of titanium tetrachloride was added dropwise at 0° C. and stirred overnight at room temperature. After filtration, the THF solution was evaporated and the product was extracted from the residue. The product has the formula: ##STR11##

Workup

  1. filtrationAfter filtration
  2. customthe THF solution was evaporated
  3. extractionthe product was extracted from the residue

Sources & evidence

ORD record
ord-2501817945c54aa5b65538cc607e9ea1
Source dataset
uspto-grants-1997_06
Patent number
US05637660

Reaction notes

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