Hydrochloric Acid → 4-Methyl-2-[3-(1-methyl-piperidin-4-yl)-propylamino]-pyrimidine-5-carbonitrile

HRID 168338Notes

Reaction equation

HRID 168338 reaction equation
[C:8](#[N:9])[c:10]1[c:11]([CH3:30])[n:12][c:13]([N:16]([C:17](=[O:18])[CH3:19])[CH2:20][CH2:21][CH2:22][CH:23]2[CH2:24][CH2:25][N:26]([CH3:29])[CH2:27][CH2:28]2)[n:14][cH:15]1.[CH3:1][CH2:2][O:3][C:4]([CH3:5])=[O:6].[ClH:31].[OH2:7]>>[C:8](#[N:9])[c:10]1[c:11]([CH3:30])[n:12][c:13]([NH:16][CH2:20][CH2:21][CH2:22][CH:23]2[CH2:24][CH2:25][N:26]([CH3:29])[CH2:27][CH2:28]2)[n:14][cH:15]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 8857Ethyl AcetateHCID 68527494N-(5-cyano-4-methyl-pyrimidin-2-yl)-N-[3-(1-methyl-piperidin-4-yl)-propyl]-acetamide

Product 1

HCID 445457774-Methyl-2-[3-(1-methyl-piperidin-4-yl)-propylamino]-pyrimidine-5-carbonitrile

Sources & evidence

ORD record
ord-8d33c31900944e70853dd8babcdb15cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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