Chloride → 5-Bromo-1-methyl-3-(5-(4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-ylamino)pyridin-2(1H)-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([N:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[cH:15][cH:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1.[C:28]([BH3-:29])#[N:30].[CH3:33][OH:34].[Cl-:35].[Cl-:37].[Na+:31].[O:23]1[CH2:24][C:25](=[O:27])[CH2:26]1.[OH2:32].[Zn+2:36]>>[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([N:17]3[CH2:18][CH2:19][N:20]([CH:25]4[CH2:24][O:23][CH2:26]4)[CH2:21][CH2:22]3)[cH:15][cH:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-b421d1f72a2e4766ad8d3c23566738da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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