Benzaldehyde → HCID 45050441, compound

HRID 1683966Notes

Reaction equation

[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:9][O:10][C:11](=[O:18])[CH2:12][CH2:13][C:14]([O:16][CH3:17])=[O:15]>>[CH3:9][O:10][C:11](=[O:18])[CH2:12]/[C:13](/[C:14]([O:16][CH3:17])=[O:15])=[CH:1]/[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 7820Dimethyl Succinate

Product 1

HCID 45050441HCID 45050441, compoundYield 4.9%

Procedure

Benzaldehyde (21.2 g) and succinic acid dimethyl ester (40.9 g) are treated in the same manner as in Reference Example 1, and the resulting product is purified by silica gel column chromatography to give (Z)-3-methoxycarbonyl-4-phenyl-3-butenoic acid methyl ester (2.3 g) as colorless syrup.

Workup

customthe resulting product is purified by silica gel column chromatography

Sources & evidence

ORD record: ord-0744193b23f94874828e643f521368ff
Source dataset: uspto-grants-1997_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05639789

Reaction notes

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