反应详情

A 15 ml tetrahydrofuran-toluene (1:1) solution of 1.0M 4-fluorophenyl zinc chloride was dripped into a mixture of 4.20 g of 4-(4-iodophenyl)-1-phenyl-1-n-propyl-1-silacyclohexane, 30 mg of tetrakis (triphenylphosphine) palladium(0) and 30 ml of tetrahydrofuran. After stirring for 8 hours at room temperature, the mixture was poured into a saturated aqueous solution of ammonium chloride and extraction was conducted using ethyl acetate. Using conventional washing, drying and concentration processes, 4-(4-(4-fluorophenyl)phenyl)-1-phenyl-1-n-propyl-1-silacyclohexane was obtained.

1. customdrying
2. concentrationconcentration processes