反应详情

25.6 g (0.048 mol) of 1-tetrahydropyranyloxyhentriacont-10-yne of Example 8 were dissolved in a mixture of 100 ml of THF and 50 ml of methanol, and a catalytic amount (spatula tipful) of p-toluenesulfonic acid monohydrate was added at room temperature. After 3 h at room temperature, the reaction mixture was poured into 1.5 1 of water and stirred for 30 min. The product was filtered off with suction, washed with water and dried under high vacuum.

1. filtrationThe product was filtered off with suction
2. washwashed with water
3. customdried under high vacuum