反应详情

To a suspension of 3,6-dichloropyridazine-4-carboxylic acid (1.16 g, 6 mmol) in toluene (20 mL) were added DMF (2 drops) and SOCl2 (4 mL) and the mixture was heated at reflux temperature for 3 h. The volatiles were removed and the residue was stripped with toluene. The resulting brown oil (3,6-dichloropyridazine-4-carbonyl chloride) was used without purification.

1. temperaturethe mixture was heated
2. temperatureat reflux temperature for 3 h
3. customThe volatiles were removed
4. customThe resulting brown oil (3,6-dichloropyridazine-4-carbonyl chloride) was used without purification