Acetate → 2-[(2,5-Dichloro-4-pyridinyl)amino]-N-methylbenzamide

HRID 168535Notes

Reaction equation

HRID 168535 reaction equation
[C:21](=[O:22])([O-:23])[O-:24].[CH3:27][C:28]1([CH3:29])[c:30]2[cH:31][cH:32][cH:33][c:34]([P:35]([c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[c:42]3[cH:43][cH:44][cH:45][cH:46][cH:47]3)[c:48]2[O:49][c:50]2[c:51]1[cH:52][cH:53][cH:54][c:55]2[P:56]([c:57]1[cH:58][cH:59][cH:60][cH:61][cH:62]1)[c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:9])[c:6]([I:8])[cH:7]1.[Cl:84][CH2:85][Cl:86].[Cs+:25].[Cs+:26].[NH2:10][c:11]1[c:12]([C:13](=[O:14])[NH:15][CH3:16])[cH:17][cH:18][cH:19][cH:20]1.[O-:76][C:77]([CH3:78])=[O:79].[O-:80][C:81]([CH3:82])=[O:83].[O:69]1[CH2:70][CH2:71][O:72][CH2:73][CH2:74]1.[Pd+2:75]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:9])[c:6]([NH:10][c:11]2[c:12]([C:13](=[O:14])[NH:15][CH3:16])[cH:17][cH:18][cH:19][cH:20]2)[cH:7]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 6344DichloromethaneHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 3080722-Amino-N-methylbenzamideHCID 6360441,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine)HCID 534009652,5-Dichloro-4-iodopyridine

Product 1

HCID 575168912-[(2,5-Dichloro-4-pyridinyl)amino]-N-methylbenzamide

Sources & evidence

ORD record
ord-9eb92e509fb648a88388e2606dc851fd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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