2-Aminothiazole → HCID 59513994, compound

HRID 1685594Notes

Reaction equation

HRID 1685594 reaction equation
CO[C:3]([C:5]1[C:13]2[C:8](=[CH:9][N:10]=[CH:11][CH:12]=2)[NH:7][CH:6]=1)=[O:4].[CH:14]1([CH2:17]Br)[CH2:16][CH2:15]1.[NH2:19][C:20]1[S:21][CH:22]=[CH:23][N:24]=1>>[S:21]1[CH:22]=[CH:23][N:24]=[C:20]1[NH:19][C:3]([C:5]1[C:13]2[C:8](=[CH:9][N:10]=[CH:11][CH:12]=2)[N:7]([CH2:17][CH:14]2[CH2:16][CH2:15]2)[CH:6]=1)=[O:4]

Participants

4

Reactant 3

HCID 21552-AminothiazoleHCID 81503BromomethylcyclopropaneHCID 54759246Methyl 1H-pyrrolo[2,3-c]pyridine-3-carboxylate

Product 1

HCID 59513994HCID 59513994, compound

Procedure

Starting material: 1H-Pyrrolo[2,3-c]pyridine-3-carboxylic acid methyl ester, R5X=cyclopropyl-methylbromide; NH2A=2-aminothiazole

Sources & evidence

ORD record
ord-85931f8a41f14cc8bd7545776980fd3f
Source dataset
uspto-grants-2012_04
Patent number
US08148413B2

Reaction notes

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