Benzyl Bromide → Indole

HRID 1685595Notes

Reaction equation

HRID 1685595 reaction equation
C(OC([C:6]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][CH:7]=1)=O)C.C(Br)C1C=CC=CC=1.C(OC(=O)CCC1N=C(N)SC=1)C>>[NH:8]1[C:9]2[C:14](=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH:6]=[CH:7]1

Participants

4

Reactant 3

HCID 7498Benzyl BromideHCID 247965Ethyl Indole-3-carboxylateHCID 11310165Ethyl 3-(2-amino-1,3-thiazol-4-yl)propanoate

Product 1

HCID 798Indole

Procedure

Indole-3-carboxylic acid ethyl ester, R5X=benzyl bromide, NH2A=3-(2-amino-thiazol-4-yl)-propionic acid ethyl ester

Sources & evidence

ORD record
ord-82f01dddda30492fab5d74fc34d3f6c5
Source dataset
uspto-grants-2012_04
Patent number
US08148413B2

Reaction notes

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