反应详情

The product from example 25 step (iv) (1.0 g) was dissolved in dry DMF (10 ml) and treated with iodomethane (0.6 ml) and potassium carbonate (1.25 g). The mixture was stirred at room temperature overnight. The mixture was diluted with water, extracted with ether, dried (MgSO4) and evaporated under reduced pressure to give an oil. The oil was purified by flash column chromatography (eluent 2:1 diethylether/isohexane) (1.30 g).

1. extractionextracted with ether
2. dry with materialdried (MgSO4)
3. customevaporated under reduced pressure
4. customto give an oil
5. customThe oil was purified by flash column chromatography (eluent 2:1 diethylether/isohexane) (1.30 g)