Bicarbonate Ion → Benzyl 4-[1-(ethoxycarbonyl)-3-oxopropyl]piperidine-1-carboxylate

HRID 168886Notes

Reaction equation

HRID 168886 reaction equation
[C:44](=[O:45])([OH:46])[O-:47].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]([CH2:7][CH:8]=[CH2:9])[CH:10]1[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:14][CH2:15]1.[I+3:26]([O-:27])([O-:28])([O-:29])[O-:30].[Na+:31].[Na+:42].[Na+:43].[Na+:48].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[OH2:37].[S:38]([O-:39])([O-:40])=[O:41]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]([CH2:7][CH:8]=[O:27])[CH:10]1[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][CH2:19][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[CH2:14][CH2:15]1

Participants

8

Reactant 7

HCID 769Bicarbonate IonHCID 923Sodium ion4×HCID 962WaterHCID 1099SulfiteHCID 8028TetrahydrofuranHCID 167232PeriodateHCID 67441606Ethyl 1-[(phenylmethoxy)carbonyl]-α-2-propen-1-yl-4-piperidineacetate

Product 1

HCID 86616780Benzyl 4-[1-(ethoxycarbonyl)-3-oxopropyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-4a9403160fec43d08783de7ab6844909
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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