Ethyl Acetate → 4-(Azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid (6-cyclopropyl-2-phenyl-imidazo[1,2-a]pyridin-7-yl)-amide

HRID 168936Notes

Reaction equation

HRID 168936 reaction equation
[CH2:1]([P:2]([OH:3])([OH:4])=[O:5])[CH2:6][CH3:7].[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[CH:8]1([c:11]2[c:12]([NH2:26])[cH:13][c:14]3[n:15]([cH:16]2)[cH:17][c:18](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[n:19]3)[CH2:9][CH2:10]1.[N:27]1([C:31](=[O:32])[c:33]2[c:34]([C:39](=[O:40])[OH:41])[n:35]([CH3:38])[n:36][cH:37]2)[CH2:28][CH2:29][CH2:30]1>>[CH:8]1([c:11]2[c:12]([NH:26][C:39]([c:34]3[c:33]([C:31]([N:27]4[CH2:28][CH2:29][CH2:30]4)=[O:32])[cH:37][n:36][n:35]3[CH3:38])=[O:40])[cH:13][c:14]3[n:15]([cH:16]2)[cH:17][c:18](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[n:19]3)[CH2:9][CH2:10]1

Participants

6

Reactant 5

HCID 8857Ethyl AcetateHCID 81531DiisopropylethylamineHCID 204484Propylphosphonic acidHCID 58446922HCID 58446922, compoundHCID 670417926-Cyclopropyl-2-phenyl-imidazo[1,2-a]pyridin-7-ylamine

Product 1

HCID 510348134-(Azetidine-1-carbonyl)-2-methyl-2H-pyrazole-3-carboxylic acid (6-cyclopropyl-2-phenyl-imidazo[1,2-a]pyridin-7-yl)-amide

Sources & evidence

ORD record
ord-b665ee714dde4f85882ce8e536a4cfe4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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