Triethylamine → HCID 86654369, compound

HRID 1689852Notes

Reaction equation

HRID 1689852 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][OH:11])=[CH:5][C:4]=1[CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].C(N(CC)CC)C.[CH3:24][S:25](Cl)(=[O:27])=[O:26]>ClCCl>[CH3:24][S:25]([O:11][CH2:10][CH2:9][C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[C:4]([CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH:5]=1)(=[O:27])=[O:26]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 66907575HCID 66907575, compound

Product 1

HCID 86654369HCID 86654369, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1.2 g (0.0054 mol) of the compound 2d) from the previous step, 20 ml of dichloromethane, 0.75 ml (0.0054 mol) of triethylamine and, at 0-5° C., 0.42 ml (0.0054 mol) of methanesulfonyl chloride are placed in a round-bottom flask.

Sources & evidence

ORD record
ord-b750f0d0269544398bbf95644a411b2e
Source dataset
uspto-grants-2012_04
Patent number
US08153637B2

Reaction notes

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