3-Chloroaniline → HCID 66905477, compound

HRID 1690599Notes

Reaction equation

HRID 1690599 reaction equation
Cl[C:2]1[N:3]([C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)[N:4]=[C:5]2[C:10]=1[CH:9]=[CH:8][C:7]([F:11])=[CH:6]2.[Cl:19][C:20]1[CH:21]=[C:22]([NH2:26])[CH:23]=[CH:24][CH:25]=1>CN1CCCC1=O>[Cl:19][C:20]1[CH:21]=[C:22]([NH:26][C:2]2[N:3]([C:12]3[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=3)[N:4]=[C:5]3[C:10]=2[CH:9]=[CH:8][C:7]([F:11])=[CH:6]3)[CH:23]=[CH:24][CH:25]=1

Participants

4

Reactant 2

HCID 79323-ChloroanilineHCID 66905406HCID 66905406, compound

Product 1

HCID 66905477HCID 66905477, compound

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

In analogy to the procedure described in example 4.1, 3-chloro-2-(4-chloro-phenyl)-6-fluoro-2H-indazole (example 40.2) was reacted with 3-chloro-phenylamine ([108-42-9]) in N-methyl 2-pyrrolidone for 72 h at 175° C. in a sealed tube to give the title compound as colorless crystals. MS: m/e=372.1 [M+H+].

Sources & evidence

ORD record
ord-f6bc1cde18af4234a384b61fa499fba2
Source dataset
uspto-grants-2012_04
Patent number
US08153663B2

Reaction notes

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