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HRID1692571

反应详情

EQUATION

反应方程式

HRID 1692571 的结构方程式

REACTANTS

反应物

2
结构：CCO
HCID702

Ethanol

C2H6O

结构：C[Si](C)(C)CNC(=O)c1ccc(C(Br)Br)c(C(F)(F)F)c1
HCID58270976

未命名化合物

PRODUCTS

生成物

1
结构：C[Si](C)(C)CNC(=O)c1ccc(C=O)c(C(F)(F)F)c1
HCID58270963

未命名化合物

收率 100%

AUXILIARIES

试剂、催化剂与溶剂

3
结构：O=[N+]([O-])[O-].[Ag+]
催化剂HCID24470

Silver nitrate

AgNO3

结构：O
溶剂HCID962

Water

H2O

结构：COC(C)(C)C
溶剂HCID15413

Methyl tert-butyl ether

C5H12O

PROCEDURE

实验过程

4-(dibromomethyl)-3-(trifluoromethyl)-N-[(trimethylsilyl)methyl]benzamide (22.0 g, 49.1 mmol) and AgNO3 (16.7 g, 98.3 mmol) in EtOH and H2O were refluxed for 2 hours, then diluted with t-BuOMe and washed with brine. Dried over MgSO4 and evaporation yielded the product (15.0 g, 100%).

WORKUP

后处理

  1. washwashed with brine
  2. dry with materialDried over MgSO4 and evaporation