Benzyl Isothiocyanate → HCID 11666764, compound

HRID 1693577Notes

Reaction equation

HRID 1693577 reaction equation
[CH2:1]([N:8]=[C:9]=[S:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:11]([N:19]=[C:20]=[O:21])[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.C([O:24]CC)C>>[CH2:11]([N:19]1[C:20](=[O:21])[N:8]([CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[C:9](=[O:24])[S:10]1)[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 3

HCID 2346Benzyl IsothiocyanateHCID 3283Diethyl EtherHCID 160602Phenethyl isocyanate

Product 1

HCID 11666764HCID 11666764, compound

Procedure

Reagents: Benzyl-isothiocyanate (6.5 mmol, 0.85 mL), phenethylisocyanate (6.5 mmol, 0.89 mL) and SO2Cl2 (6.5 mmol, 0.52 mL) in diethyl ether (25 mL). Isolation: solvent evaporation. Purification: silica gel column chromatography (AcOEt/hexane, 1:4).

Workup

  1. customIsolation: solvent evaporation
  2. customPurification

Sources & evidence

ORD record
ord-0571cadd15034c17b2d6f85711cbfdff
Source dataset
uspto-grants-2012_04
Patent number
US08158661B2

Reaction notes

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