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HRID1696742

反应详情

EQUATION

反应方程式

HRID 1696742 的结构方程式

REACTANTS

反应物

2
结构：Br
HCID260

Hydrogen Bromide

BrH

结构：N#Cc1c(C(F)(F)F)cc(-c2ccc(C(F)(F)F)cc2)[nH]c1=O
HCID53256598

2-Oxo-4-(trifluoromethyl)-6-[4-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carbonitrile

C14H6F6N2O

PRODUCTS

生成物

1
结构：O=c1cc(C(F)(F)F)cc(-c2ccc(C(F)(F)F)cc2)[nH]1
HCID57468622

未命名化合物

收率 136.9%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCC(=O)O
溶剂HCID1032

未命名化合物

PROCEDURE

实验过程

The compound was prepared from 2-oxo-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-1,2-dihydro-pyridine-3-carbonitrile (42 g, 126 mmol) and 48% aqueous HBr in propionic acid according to general procedure Ia, step 2 protocol b. Obtained as a white solid (52.98 g, 88%). MS (ISP) 308.3 [(M+H)+]; mp 203-204° C.