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HRID1697025

反应详情

EQUATION

反应方程式

HRID 1697025 的结构方程式

REACTANTS

反应物

3
结构：NCCN1CCCCC1
HCID33944

N-(2-Aminoethyl)piperidine

C7H16N2

结构：CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(N[C@H](CO)Cc4ccccc4)nc32)[C@H](O)[C@@H]1O
HCID67019378

未命名化合物

结构：CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCc4cccc5ccccc45)nc(Cl)nc32)[C@H](O)[C@@H]1O.O=C(O)C(F)(F)F
HCID86622652

未命名化合物

PRODUCTS

生成物

1
结构：CCC(=O)N[C@H]1C[C@@H](n2cnc3c(NCc4cccc5ccccc45)nc(NCCN4CCCCC4)nc32)[C@H](O)[C@@H]1O.O=C(O)C(F)(F)F
HCID67019398

未命名化合物

PROCEDURE

实验过程

This compound is prepared analogously to N-{(1S,2R,3S,4R)-4-[6-(2,2-diphenyl-ethylamino)-2-((S)-1-hydroxymethyl-2-phenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide (Example 16) by replacing N-{(1S,2R,3S,4R)-4-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl}-propionamide (Example 4) with N-((1S,2R,3S,4R)-4-{2-chloro-6-[(naphthalen-1-ylmethyl)-amino]-purin-9-yl}-2,3-dihydroxy-cyclopentyl)-propionamide trifluoroacetate (Example 50) and by replacing (S)-2-amino-3-phenyl-propan-1-ol with 2-piperidin-1-yl-ethylamine.