Methanesulfonyl chloride → HCID 22246767, compound

HRID 1699037Notes

Reaction equation

HRID 1699037 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([Cl:12])[CH:11]=1)[O:5][CH2:6][CH2:7][NH2:8].[CH3:13][S:14](Cl)(=[O:16])=[O:15]>CCN(CC)CC>[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]=[C:10]([Cl:12])[CH:11]=1)[O:5][CH2:6][CH2:7][NH:8][S:14]([CH3:13])(=[O:16])=[O:15]

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 499912-(3,5-Dichlorophenoxy)ethylamine

Product 1

HCID 22246767HCID 22246767, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound was prepared from 2-(3,5-dichloro-phenoxy)-ethylamine, Et3N, and methanesulfonyl chloride using the procedure described in Step 2 of Preparation A1. Recrystallization from EtOH provided the title compound. 1HNMR (400 MHz, CDCl3) δ6.93 (m, 1H), 6.74 (m, 2H), 5.09 (m, 1H), 4.01 (t, 2H), 3.47 (q, 2H), 2.96 (s, 3H).

Workup

  1. customRecrystallization from EtOH

Sources & evidence

ORD record
ord-24b8ac2f76f44da986b78595515a6f77
Source dataset
uspto-grants-2002_02
Patent number
US06344485B1

Reaction notes

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