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HRID1699221

反应详情

EQUATION

反应方程式

HRID 1699221 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)(C)OC(=O)NCCN1C(=O)c2ccccc2C1=O
HCID11483141

tert-Butyl [2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl]carbamate

C15H18N2O4

PRODUCTS

生成物

1
结构：Cl.NCCN1C(=O)c2ccccc2C1=O
HCID22063849

2-(2-Aminoethyl)-1H-isoindole-1,3(2H)-dione--hydrogen chloride (1/1)

C10H11ClN2O2

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

A mixture of N-(2-tert-butoxycarbonylaminoethyl)phthalimide (2.5 g) and 4N solution of hydrogen chloride in ethyl acetate (25 ml) was stirred for 1 hour at ambient temperature. The resulting precipitates were collected by filtration and washed with ethyl acetate to give N-(2-aminoethyl)phthalimide hydrochloride (1.89 g) as colorless crystals.

WORKUP

后处理

  1. customThe resulting precipitates
  2. filtrationwere collected by filtration
  3. washwashed with ethyl acetate