反应详情

温度

20 °C

Dihydroartemisinin (50 mg) was dissolved in dry ethanol (3 ml). Add 2 ml of triethylorthoformate and (25 mg) of p-toluenesulphonic acid. The reaction mixture was stirred at room temperature (20° C.) for 30 min. 50 ml of water was added in the reaction mixture The reaction product was extracted by dichloromethane (30 mil×3). The dichloromethane extract was dried over anhydrous sodium sulphate and evaporation of solvent under vacuum at 40° C. and yielded the arteether (52 mg).

1. extractionwas extracted by dichloromethane (30 mil×3)
2. extractionThe dichloromethane extract
3. dry with materialwas dried over anhydrous sodium sulphate and evaporation of solvent under vacuum at 40° C.