Hydrochloric Acid → 2-Amino-7-phenyl-7,8-dihydro-6H-quinazolin-5-one

HRID 169992Notes

Reaction equation

HRID 169992 reaction equation
[CH3:1][N:2]([CH:3]=[C:4]1[C:5](=[O:6])[CH2:7][CH:8]([c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[CH2:15][C:16]1=[O:17])[CH3:18].[ClH:19].[NH2:20][C:21]([NH2:22])=[NH:23].[NH2:30][c:31]1[n:32][c:33]2[c:38]([cH:39][n:40]1)[C:37](=[O:41])[CH2:36][CH:35]([c:42]1[cH:43][cH:44][c:45]([Cl:48])[cH:46][cH:47]1)[CH2:34]2.[Na+:24].[Na+:25].[O-:26][C:27](=[O:28])[O-:29]>>[NH2:30][c:31]1[n:32][c:33]2[c:38]([cH:39][n:40]1)[C:37](=[O:41])[CH2:36][CH:35]([c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1)[CH2:34]2

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 3520GuanidineHCID 19660Carbonate IonHCID 27723712-amino-7-(4-chlorophenyl)-7,8-dihydroquinazolin-5(6H)-oneHCID 108901102-Dimethylaminomethylene-5-phenyl-cyclohexane-1,3-dione

Product 1

HCID 27723882-Amino-7-phenyl-7,8-dihydro-6H-quinazolin-5-one

Sources & evidence

ORD record
ord-8189cc0efc53496eba8e6fc315211907
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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