Dimethylformamide → tert-butyl N-[1-(4-bromophenyl)-4-[3-[3-(3-methoxypropyl)imidazo[4,5-c]pyridin-2-yl]piperidin-1-yl]-4-oxobutan-2-yl]carbamate

HRID 170102Notes

Reaction equation

HRID 170102 reaction equation
[Br:21][c:22]1[cH:23][cH:24][c:25]([CH2:28][CH:29]([CH2:30][C:31](=[O:32])[OH:33])[NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])[cH:26][cH:27]1.[CH3:1][O:2][CH2:3][CH2:4][CH2:5][n:6]1[c:7]([CH:15]2[CH2:16][NH:17][CH2:18][CH2:19][CH2:20]2)[n:8][c:9]2[c:10]1[cH:11][n:12][cH:13][cH:14]2.[CH3:42][N:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1.[O:73]=[CH:74][N:75]([CH3:76])[CH3:77].[P-:49]([F:50])([F:51])([F:52])([F:53])([F:54])[F:55].[n:56]1([O:57][C:58]([N:59]([CH3:60])[CH3:61])=[N+:62]([CH3:63])[CH3:64])[c:65]2[n:66][cH:67][cH:68][cH:69][c:70]2[n:71][n:72]1>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][n:6]1[c:7]([CH:15]2[CH2:16][N:17]([C:31]([CH2:30][CH:29]([CH2:28][c:25]3[cH:24][cH:23][c:22]([Br:21])[cH:27][cH:26]3)[NH:34][C:35](=[O:36])[O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:32])[CH2:18][CH2:19][CH2:20]2)[n:8][c:9]2[c:10]1[cH:11][n:12][cH:13][cH:14]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 53397991Boc-3-amino-4-(4-bromo-phenyl)-butyric acidHCID 667856133-(3-Methoxypropyl)-2-piperidin-3-ylimidazo[4,5-c]pyridine

Product 1

HCID 77190875tert-butyl N-[1-(4-bromophenyl)-4-[3-[3-(3-methoxypropyl)imidazo[4,5-c]pyridin-2-yl]piperidin-1-yl]-4-oxobutan-2-yl]carbamate

Sources & evidence

ORD record
ord-c049ed2aa4b045d3a886bcfa5b2e6d4b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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