p-Bromochlorobenzene → HCID 86736859, compound

HRID 1701352Notes

Reaction equation

HRID 1701352 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][CH:3]=1.[Mg].[Cl:10][C:11]1[CH:16]=[CH:15][C:14]([Mg]Br)=[CH:13][CH:12]=1.[Cl-].[Cd+2:20].[Cl-]>CCOCC>[Cd:20].[Cl:8][C:5]1[CH:6]=[CH:7][CH:2]=[CH:3][CH:4]=1.[Cl:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

6

Reactant 4

HCID 7806p-BromochlorobenzeneHCID 24633Cadmium chloride, dihydrateHCID 5462224MagnesiumHCID 178478191HCID 178478191, compound

Product 1

HCID 86736859HCID 86736859, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

A solution of 95 g of p-bromochlorobenzene in 250 cc of ether was added to 15 g of magnesium in 250 cc of ether while maintaining the reaction mixture at reflux. The mixture was stirred for 11/2 hours at room temperature to obtain a solution containing 0.78 mole per liter of p-chlorophenyl magnesium bromide. 17.9 g of cadmium chloride were added to 230 cc of the acid solution and after stirring for 10 minutes, the ether was distilled off while maintaining the volume constant by addition of benzene to obtain a benzene solution of bis-(p-chlorobenzene) cadmium compound.

Workup

  1. temperaturewhile maintaining the reaction mixture
  2. temperatureat reflux
  3. customto obtain a solution
  4. stirringafter stirring for 10 minutes
  5. distillationthe ether was distilled off
  6. temperaturewhile maintaining the volume
  7. additionconstant by addition of benzene

Sources & evidence

ORD record
ord-2205832dcaa241e693f93d54f70368a2
Source dataset
uspto-grants-1980_03
Patent number
US04192890

Reaction notes

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