1-(3-chlorophenyl)-3-hydroxyurea → HCID 13071780, compound

HRID 1701480Notes

Reaction equation

HRID 1701480 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]([NH:11][OH:12])=[O:10])[CH:5]=[CH:6][CH:7]=1>C(C(CC)=O)C>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:2]([CH2:3][CH3:4])([CH2:7][CH3:6])[O:12][NH:11][C:9]2=[O:10])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 2695031-(3-chlorophenyl)-3-hydroxyurea

Product 1

HCID 13071780HCID 13071780, compound

Reagents, catalysts & solvents 1

HCID 7288Ethyl ketoneSolvent

Conditions

Temperature
90 °C

Procedure

18.7 g. of N-(3-chlorophenyl)-N'-hydroxy-urea are added to 116 g. of diethyl ketone. The reaction is stirred at 90° C. for 1 hour. The reaction mixture is then evaporated to dryness and the residue is recrystallized from a mixture of methanol and water.

Workup

  1. customThe reaction mixture is then evaporated to dryness
  2. customthe residue is recrystallized from a mixture of methanol and water

Sources & evidence

ORD record
ord-82f7474bc18e4c51b89226b8f96ff34c
Source dataset
uspto-grants-1980_03
Patent number
US04193922

Reaction notes

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