Potassium Carbonate → HCID 54035734, compound

HRID 1701716Notes

Reaction equation

HRID 1701716 reaction equation
[C:1]1([OH:11])[C:10]2[CH2:9][CH2:8][CH2:7][CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.C(=O)([O-])[O-].[K+].[K+].Br[CH2:19][C:20]([O:22][CH3:23])=[O:21]>CC(=O)CC>[C:1]1([O:11][CH2:19][C:20]([O:22][CH3:23])=[O:21])[C:10]2[CH2:9][CH2:8][CH2:7][CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 60984Methyl bromoacetateHCID 682585,6,7,8-Tetrahydro-1-naphthol

Product 1

HCID 54035734HCID 54035734, compound

Reagents, catalysts & solvents 1

HCID 6569Methyl Ethyl KetoneSolvent

Procedure

10 g 5,6,7,8-tetrahyro-1-naphthol are dissolved in 150 ml 2-butanone and then 18.5 g potassium carbonate and 12.3 g methyl bromoacetate are introduced into the mixture. After having been refluxed for 24 hours, the mixture is filtered, the solvent evaporated under reduced pressure and after removal of the starting phenol soluble in aqueous basic medium, 13.1 g of final product are distilled.

Workup

  1. temperatureAfter having been refluxed for 24 hours
  2. filtrationthe mixture is filtered
  3. customthe solvent evaporated under reduced pressure
  4. customafter removal of the starting phenol soluble in aqueous basic medium, 13.1 g of final product
  5. distillationare distilled

Sources & evidence

ORD record
ord-6cd91dddd17f4838aca575df6b89fc97
Source dataset
uspto-grants-1980_03
Patent number
US04195093

Reaction notes

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