Glycol monoethyl ether → HCID 20525890, compound

HRID 1702683Notes

Reaction equation

HRID 1702683 reaction equation
Cl.[CH2:2]([NH:18][C:19]1[CH:29]=[CH:28][C:22]([CH2:23][CH2:24][C:25](Cl)=[O:26])=[CH:21][CH:20]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[CH2:30]([O:32][CH2:33][CH2:34][OH:35])[CH3:31]>CN(C)C1C=CN=CC=1.C(Cl)Cl>[CH2:2]([NH:18][C:19]1[CH:29]=[CH:28][C:22]([CH2:23][CH2:24][C:25]([O:35][CH2:34][CH2:33][O:32][CH2:30][CH3:31])=[O:26])=[CH:21][CH:20]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

Participants

5

Reactant 2

HCID 8076Glycol monoethyl etherHCID 20525783HCID 20525783, compound

Product 1

HCID 20525890HCID 20525890, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 6344DichloromethaneSolvent

Procedure

Prepared as described in Example 18, 10.0 g. of 4-(hexadecylamino)hydrocinnamoyl chloride hydrochloride in 80. ml. of methylene chloride is treated with 9.5 g. of 4-dimethylaminopyridine and 2.1 g. of 2-ethoxyethanol, analogous to the method of Example 19. Workup and filtration through alumina provides 2-ethoxyethyl 4-(hexadecylamino)hydrocinnamate.

Workup

  1. customPrepared
  2. filtrationWorkup and filtration through alumina

Sources & evidence

ORD record
ord-db7b1ffb1f6b48ac9fceb73b5cb13496
Source dataset
uspto-grants-1982_09
Patent number
US04348399

Reaction notes

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