Sodium hydride → HCID 12961710, compound

HRID 1702889Notes

Reaction equation

HRID 1702889 reaction equation
[H-].[Na+].[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:14]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[C:13](=[O:21])[NH:12][CH:11]=2)=[CH:6][CH:5]=1.[CH3:22][O:23][C:24](=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]Br>CN(C=O)C>[CH3:22][O:23][C:24](=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][N:12]1[CH:11]=[C:10]([C:7]2[CH:6]=[CH:5][C:4]([Cl:3])=[CH:9][CH:8]=2)[N:14]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:13]1=[O:21]

Participants

5

Reactant 3

HCID 24758Sodium hydrideHCID 11107373Methyl 8-bromooctanoateHCID 20525408HCID 20525408, compound

Product 1

HCID 12961710HCID 12961710, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The product is produced as described in example 1 from 1.05 g of NaH (80% suspension in mineral oil), 9.5 g of 5-(4-chlorophenyl)-1-phenyl-4-imidazolin-2-one, 70 cc. of DMF, 8.3 g of 8-bromocaprylic acid methyl ester and 1.05 g of NaJ.

Workup

  1. customThe product is produced

Sources & evidence

ORD record
ord-7918fb49b8bf414a808ceb8b50c06757
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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